Friday October 14th, 2011 12:29

Dr Klein’s Demerol could have caused Jackson’s insomnia: Murray trial update

Conrad Murray

An expert in sleep medicine confirmed to the court hearing the Conrad Murray manslaughter trial yesterday that Jackson had been taking the painkiller Demerol, and that that could have been the cause of his acute insomnia. Dr Nader Kamangar also conceded that the idea that propofol be used to cure severe insomnia was not totally new, but added that the method was unproven, and certainly should not have been used in a domestic setting.

Murray, of course, is accused of causing the death of Michael Jackson by negligently administering the surgical anaesthetic propofol as a cure for insomnia. Murray’s defence argue that the singer most likely administered the fatal shot of the drug himself. They have also been keen to show that using propofol to induce sleep, while unusual, isn’t totally unheard of, that their client didn’t introduce Jackson to propofol as sleep aid anyway, and that he was actually trying to wean his patient off the drug.

They also claim that another doctor seen by Jackson regularly, dermatologist Dr Arnold Klein, was negligently prescribing the singer the Demerol that likely caused the acute insomnia that Murray was trying to cure, and that Klein should therefore also be partly liable for the late king of pop’s untimely demise. Judge Michael Pastor has refused the defence’s application to call Klein as a witness – ruling his testimony would not be sufficiently relevant – but the other doctor’s alleged role was mentioned by defence attorneys during their opening remarks, and again by Murray himself in a police interview, a recording of which was played in court this week.

One of the prosecution’s final witnesses, Kamangar’s testimony was most interesting when being questioned by defence lawyers. The sleep expert confirmed that Michael Jackson’s records showed he had been receiving Demerol from Dr Klein, adding: “I usually avoid using Demerol [with my patients, because] it can actually activate someone, make them more hyper or excited, create more stimulation”.

Could it cause insomnia, defence attorney Michael Flanagan asked. “It certainly can,” Kamangar replied. Was Jackson addicted to Dermerol? Kamangar said he did not have enough information to answer that question.

Moving on Flanagan asked Kamangar about a Chinese study in 2010 which looked into the use of propofol to induce sleep where patients suffered from acute insomnia. Didn’t that survey show that propofol helped some patients, the lawyer asked. Yes, Kamangar said, but it was a very experimental survey and did not in itself justify using the drug as a sleep aid, even in a hospital, and certainly not in a patient’s home. According to Reuters, the doctor concluded: “[In that report], even the authors in the end explain that this is just a very preliminary experiment and it needs way more studies to even imagine using this drug for [insomnia]“.

The case continues.

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  • Moi

    As someone following the Jackson trial closely, I wish that the fact
    that Demerol had absolutely nothing to do with Jackson’s death was more
    widely reported. Instead, the illogical, irrelevant “Demerol defense”
    is being passed around by news organizations without the proper context.

    According to Jackson’s toxicology report, there was no Demerol — or
    it’s long-lasting metabolite — found in either Jackson’s blood or
    urine at the time of his death. This is important information, because
    the average life-span of the longest Demerol metabolite is roughly a
    week — and Demerol addicts typically need the drug on a daily basis.
    The fact that Jackson had no trace of Demerol in his blood or his urine
    (which would show if the drug had passed through the body) is very
    significant and cannot be understated, in my opinion.

    Another damning fact is that long-term Demerol abuse — as Murray
    alleges — should cause liver changes (ex. fatty liver). Michael
    Jackson’s liver was in perfect condition, according to the coroner and
    Jackson’s autopsy report.

    That Murray’s defense attorneys are trying to shift blame from
    Murray to other doctors is despicable. If Murray was so concerned about
    the cause of Jackson’s insomnia, he should have conducted the necessary
    tests and physical/psychological analysis. But he didn’t. Murray also
    stated in his police interview that he knew Jackson was seeing Klein. It
    is ridiculous for Murray to now act like he was clueless about all of
    these things.

    Furthermore . . . dermatologist Dr. Arnold Klein long ago turned his
    20-years-wortth of medical records on Jackson over to the police. Klein
    was also thoroughly investigated by the DEA. Nothing illegal was found
    and he was cleared. The fact is, Klein had only administered Demerol to
    Jackson a handful of times for painful cosmetic procedures (such as
    dermal fillers, etc.). And Jackson had only visited Klein’s clinic six
    times in the month of June — the last time being three to four days
    before his death.

    In short: Klein had absolutely nothing to do with the events of June 25, 2009. That’s all on Murray.